Dear Daniel Congrave:

Thank you for the information about the process, if you have any reference, could you kindly let me know the reference to follow with exact moles and quantities to be used to carry out the reaction.

check this articles:

Synlett 1998; 1998(4): 431-433

Journal of Heterocyclic Chemistry Volume 44, Issue 6, pages 1235–1246

European Journal of Organic Chemistry Volume 2009, Issue 21, pages 3544–3553

use hydrazine hydrate and ethyl acetate reflux for3hrs and start ethyl acetate recovery. residue left will be acetylhydrazide 

@ All:

Thanks to all individually for the details and information about the process.

@ Antorio Latorre:  Thanks for the references, I will try to get those articles.

@ Daniel Congrave:  Thanks for the detials of the Patent, yep as you said there might be the risk of the formation of a dimer means diacetylation chances will be high, but the process is helpful.

@ Dr. Shiv Kumar Yadav:

Thanks for the said method.  How come we will come to know whether the product is formed or not after 3 hr of reflux.......? Need to monitor through TLC or any other method to confirm the completion of the reaction.......? let me know.

Actually today I had kept reflux at 85-90oC by taking 0.1 mole of ethylacetate+0.2 moles of hydrazine hydrate+ 40 ml of ethanol + 3-4 drops of Conc. H2SO4, completed 4hr-30min reflux. Monitored the reaction every hour with TLC. Still I need to continue the reaction.

Thanks to all once again

Nagendra Babu M.

Realize your synthesis using Ac2O in pyridine, or better in DCM by action of Ac2O with eqimolar Et3N in catalytic presence of DMAP.