Nagendra Babu Mennuru

8 Questions 15 Answers 0 Followers

Questions related from Nagendra Babu Mennuru

Is it possible to get yield more than 100% in a chemical reaction....?

Is it possible to get yield of a chemical product more than 100%...? If so, how one can defend this situation? I am working on Condensation reactions using organic solvent free synthesis. For some...

23 June 2018 2,608 21 View

What happens when the following events are noticed in Human Being?

What happens when: 1. HMGCS2 Expression is enhanced....? 2. PfA-M1 aminopeptidase is inhibited....? 3. Mcl-1 is antagonised (inhibited).....? (All these have been estimated using in-silico...

07 December 2016 565 1 View

How to calculate Woodward height of pyramid parameter 'h' and Cohen parameter 'c' for beta lactam rings?

How to calculate the Woodward Height of pyramid parameter 'h' for N-atom and Cohen parameter 'c' for beta-lactam rings and their derivatives? Is there any software or web resource to get the...

24 October 2016 9,486 2 View

Do anyone know what are the current lead molecules of interest to work on Tuberculosis or Malaria or HIV for designing new drug candidates?

Hi all, currently I am working on anti-infectives (Tb, Malaria, HIV related drugs) to design new drug candidates. I request you all, if anyone has the same research interest, kindly let me know...

05 September 2016 4,207 6 View

Could anyone help me to find novel targets for Tuberculosis which should be present only in Mycobacterium tuberculosis, but not in human beings?

In order to concentrate on new targets to treat tuberculosis, could anyone help me to find out new targets and their possible binding sites which should be present in Mycobacterium tuberculosis...

16 July 2016 5,538 4 View

Can someone let me know about the best in silico and in vitro screening methods for anti-HIV activity?

Does anyone let me know about the methods to screen anti-HIV activity for new chemical compounds which are expected to act on HIV-1 reverse transcriptase. I require both in silico as well as in...

25 March 2015 8,274 3 View

How can I acylate (E)-1-phenyl-2-(1-phenylethylidene)hydrazine or Acetophenone Phenylhydrazone?

Dear all: Do anyone let me know about the procedure of N-acylation of Acetophenone Phenylhydrazone or (E)-1-phenyl-2-(1-phenylethylidene)hydrazine using either acetic anhydride or acetyl chloride...

14 March 2015 4,546 6 View

Can anyone list different compound classes other than Coumarins, Chalcones, Isatins, Formazans, & etc with pharmacological interest?

I would like to know different classes of chemical compounds other than Coumarins, Chalcones, Isatins, Schiff & Mannich bases, Formazans if any which are having pharmacological importance. If...

20 February 2015 647 9 View