12 Questions 23 Answers 0 Followers
Questions related from Nagendra Babu Mennuru
Hi All: I would like to request you all to let me know the information about any organizations or institutions which perform in-vivo anti-tubercular assay of synthetic compounds as a part of...
10 January 2019 9,912 0 View
Is it possible to get yield of a chemical product more than 100%...? If so, how one can defend this situation? I am working on Condensation reactions using organic solvent free synthesis. For some...
23 June 2018 2,757 21 View
What happens when: 1. HMGCS2 Expression is enhanced....? 2. PfA-M1 aminopeptidase is inhibited....? 3. Mcl-1 is antagonised (inhibited).....? (All these have been estimated using in-silico...
07 December 2016 623 1 View
How to calculate the Woodward Height of pyramid parameter 'h' for N-atom and Cohen parameter 'c' for beta-lactam rings and their derivatives? Is there any software or web resource to get the...
24 October 2016 9,557 2 View
Hi all, currently I am working on anti-infectives (Tb, Malaria, HIV related drugs) to design new drug candidates. I request you all, if anyone has the same research interest, kindly let me know...
05 September 2016 4,237 6 View
In order to concentrate on new targets to treat tuberculosis, could anyone help me to find out new targets and their possible binding sites which should be present in Mycobacterium tuberculosis...
16 July 2016 5,619 4 View
Does anyone let me know about the methods to screen anti-HIV activity for new chemical compounds which are expected to act on HIV-1 reverse transcriptase. I require both in silico as well as in...
25 March 2015 8,351 3 View
Dear all: Do anyone let me know about the procedure of N-acylation of Acetophenone Phenylhydrazone or (E)-1-phenyl-2-(1-phenylethylidene)hydrazine using either acetic anhydride or acetyl chloride...
14 March 2015 4,585 6 View
Dear all: Can anyone let me know the procedure on how to acetylate/acylate on free amine group of Arylhydrazones (R-CH=N-NH2) using Acetic anhydride or Acetyl chloride to get Hydrazone-hydrazides...
10 March 2015 6,439 5 View
Of course, as far as my knowledge and search of literatures, Acetanilide is not much reactive compound to undergo this type of reaction at Carbonyl Carbon and there is no supporting information...
23 February 2015 3,745 8 View
I would like to know different classes of chemical compounds other than Coumarins, Chalcones, Isatins, Schiff & Mannich bases, Formazans if any which are having pharmacological importance. If...
20 February 2015 691 9 View
Hi all, I am working on O-Acylation of Phenols with 2-bromopropionyl bromide, but unfortunately I am not getting the reaction completion confirmation through TLC monitoring even after following...
15 February 2015 8,659 8 View
