How artificial colorants bind to DNA causing its degradation?

19 December 2017 1 2K Report

Food colorants Amaranth, Indigo carmine and Tartrazine had a toxic potential to human lymphocytes and seems that they bind directly to DNA, i need to know about that.

Benoit Schilter

these colorants are toxicologically well characterized, inlcuding the genotoxicity. The best would be to look at reports from internationally recognized bodies such as the WHO Joint Expert Committee on food additives (JECFA-monographs) where data are presented and reviewed with an expert conclusion on potential for genotoxicity (and mechanisms such as DNA adduct formation) and mechanisms conclusion

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