How are the process of mitochondrial biogenesis and its role in ageing and longevity?

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Christian Q. Scheckhuber

Mitochondrial biogenesis seems to be coupled to the degradation of dysfunctional mitochondria. If these processes become compromised this results in an imbalance between biogenesis and degradation so that damaged mitochondria accumulate in the cell. This is supposed to lead to cellular dysfunction and ultimately ageing.

Please refer to the publication in the attachment for more details.

With best regards, Christian

Article Coordination of mitophagy and mitochondrial biogenesis durin...

Sulaiman Amur Al Alawi

many thanks