Is there any standards or limit tresholds for the following heavy metals : Aluminum, Beryllium, Boron, Calcium, Tin, Iron, Magnesium, Manganese, Phosphorus, Potassium, Sodium, Sulphur, Thallium? Titanium and Vanadium
you can find the information in here ICH HARMONISED GUIDELINE GUIDELINE FOR ELEMENTAL IMPURITIES Q3D(R1). https://www.ema.europa.eu/en/documents/scientific-guideline/international-conference-harmonisation-technical-requirements-registration-pharmaceuticals-human-use_en-32.pdf
Toxic Characteristic Leaching Procedure (TCLP) and Waste Extraction Test (WET) are test methods that have been introduced to measure the toxicity of heavy metals in landfill conditions. These methods have introduced toxicity limits for some of the heavy metals you mentioned in your question. you can find these thresholds below
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