Is there an association between the contamination of environment by heavy metals and ABR?
there are few studies that refer to this case. any discussion about this relationship ?
Environmental contamination with Heavy metals may predispose to heavy metal resistance but not to antibiotic resistance. To have Heavy metal resistance is not as easy as to antibiotics since their action is oligodynamic action. Hence, bacteria may find it difficult to deal with four or five mechanisms of action at the same time unless low concentrations are present, giving the opportunity for bacteria to develop resistance.
Most metals are related to at least one antibiotic resistance gene in terms of full gene numbers excluding Al, Mn and Pb which they are linked to higher percentage of soil bacteria exhibiting resistance, which is in turn could be a signal of inhabitants selection ( Knapp et al., 2017).
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