I am currently writing a grant application and was thinking of proposing to use SICER for the analysis of ChIPseq data from a transcription factor that binds chromatin, but not DNA. I am not familiar with SICER and wondered if anyone has used it and for exactly what application. No wrong answers here, just trying to get a feel for how this program can help me.
Matthew Edward Thornton
I have not used SICER, but I really like RSAT. http://www.rsat.eu/ Do you think that it might suit your needs? However, I think you must get position-specific scoring matrices from TRANSFAC, but, I guess you could make your own PSSMs and use them with RSAT.
Here is their ChIP-seq paper, http://www.ncbi.nlm.nih.gov/pubmed/22836136
0 votes
0 thanks
- Badges
- Science topic
- Similar topics
- Biological Science
- Genetics
- Gene Expression
More Lawrence T Reiter's questions See All
Similar questions and discussions