I am doing a study on how a certain exposure may affect (change) biomarker profiles in human serum, i.e. at baseline compared to 1 hour after the exposure. In order to detect any change, I assume the biomarker half-lives should be short (at least less than 1 hour). Unfortunately, I struggle to find reliable and comprehensive sources (ideally a database) on half-lives of proteins/ biomarkers in human serum. (The manufacturer does not have this kind of information either).

I would be immensely grateful for any suggestions on how to find this kind of information! (without having to perform half-life experiments myself for the 150-200 proteins of interest)