Hello, in general and depending of the doses, the conformation is modified drastically from the original one. The 3D structure of a protein is disrupted and there is degradation, cross linking and aggregation of pp chains. Oxigen radicals are produced by irradiation and they produce chemical reactions with unpredictable effects. The kind of protein and Radiation doses between many other factors determine the results. In Myoglobin for example the alpha helical content is decreased and the aperiodic structure increased.The protein function is of course losted. What is the source and dose of gamma radiation?

 see these reference: Lee & Song, Journal of Biochemistry and Molecular Biology

,Vol. 35, No. 6, November 2002