There exists a complex and dynamic interaction between the heart and brain especially in the setting of negative emotions. Stress, anger, and depression have all been shown to have a significant impact on cardiac arrhythmogenesis. Not only does negatively charged emotion result in coronary ischemia, platelet activation, vasoconstriction, alteration in hemodynamics and catecholamine release but it also has a significant effect on atrial and ventricular electrical indices [1–4] (Fig.). This is not where the story ends though, as it appears that cardiac afferent feedback mechanisms result in changes in the cortical regions, insula and anterior cingulate cortices in the brain

Article Stress-induced cardiac arrhythmias: The heart–brain interaction

The violent anger and frustration frequently elicit sighing. A sigh strongly affects HR.

Evgeny

From what I have seen on a HRV monitor since 2009,  emotional variations are reflected on HRV including such emotional changes as a violent anger and frustrations. There can be interaction with provided medications, this is why it is wise to measure before and after the medications. If there is a goal to find an appropriate medications to calm down frequent violent anger and frustration, logically effect of medications can be reflected on HRV, so one appropriate can be found by an experienced researcher or a physician.