Entomogenous fungi and human cancers?

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Is bryostatin-1 a cytotoxic agent or rather an agent belonging to the targeted therapy area?

Dear Colleagues, I am searching high-impacted scientific journals giving a "crystal-clear" response to my question here above, but as yet unsuccessfully. If anyone has such articles, I would be...

07 August 2016 9,509 4 View

Does it exist ADVANCED STAGE cancers without identified genomic mutations?

Can invasive (i.e. actually malignant) cancers occur without genomic mutations? If yes, which is/are the histopathological group(s) in which it occurs? Best regards Robert

02 March 2016 10,011 16 View

How the MDR phenotype is switching on in cancer cells? It seems that this question raises more than weak interest ...

Among the unfortunately (too) large set of chemoresistance mechanisms in cancer cells is the so "popular" ABC-related pump / MDR phenotype. While there are hundreds (if not housands) of articles...

02 March 2016 9,726 13 View

Clinical Phase II to Phase III failures in oncology?

I am requesting the help of the RG community to provide me with recent (no older than 5 years) articles (from very high and only from very high ranked journals) clearly 1) indicating how many...

01 February 2016 817 20 View

Cancer cell cannibalism?

Would be "some RG Community members" so kind in providing me with articles (even if not top-ranged) about any type of chemicals able to induce ENTOSIS SPECIFICALLY in CANCER CELLS.Thank you very...

01 February 2016 8,225 4 View

And what about gliomas?

Dear Gamze, Are you envisaging also to develop your approach to cross the blood-brain-barrier in order to combat gliomas (and more specifically glioblastomas) with nanocarriers including...

01 January 1970 10,129 0 View

Does crude extraction using NaOH and Tris work well with Fungi?

I'm trying to find a DNA extraction method for fungi that does not require equipment and heating. Is there anyone who can suggest an alternative option? Thank you

08 August 2024 4,733 2 View

Is there any way to quantify bacterial and fungal cells in their mixed culture?

I am working in fungal fermentation of soybean meal and there is bacterial growth in them at times. I am trying to quantify fungal cell counts and bacterial cells; but I haven't been able to do at...

07 August 2024 7,535 4 View

Why activated CAR-Jurkat cell could not kill targets?

Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...

06 August 2024 641 2 View

How much total RNA concentration to be extracted from sorted plasma cells from bone marrow of C57BL/6 mice for RT-PCR ?

i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...

05 August 2024 8,835 1 View

How to use Density Functional Theory to calculate carrier mobilities of solid system?

Hello, everyone. I have tried to determine carrier motilities of some materials, by Density Functional Theory, using Quantum ESPRESSO. There are a few methods to do it, like a package called...

04 August 2024 8,894 1 View

Does long-term culture of murine Monocytes result in macrophage differentiation?

Hi, I am isolating monocytes from the bone marrow using the Mouse Monocyte EasySep kit. I want to treat these cells and monitor expression of specific markers over the course of 10 days. I will...

04 August 2024 7,282 2 View

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

What is fitofthora instance of potatoes?

Now research fellow used it to prevent fungus in potato,may be potatoes gene effect.

02 August 2024 180 3 View

How can I get my Granzyme B flow cytometry stain to be consistent?

I have used PE and PE-Dazzle 594 fluorochromes and have managed to get NK cells to properly show GranzymeB expression after 4 hr PMA/ionomycin stimulaton, but for some reason my CD8 cells in the...

01 August 2024 7,677 2 View

Best mask design for metal deposition aiming build a Perovskite solar cell device?

What types of mask designs for metal deposition, to be used in a PVD system, are best suited for perovskite-based solar cells?

31 July 2024 4,835 3 View

Saleh Alkarim

Hello

look at links here .

Good Luck

http://kcms.daegu.ac.kr/user/jwyun/mycodyimages/interpaper_004.pdf

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766723/pdf/kjpp-13-49.pdf

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495694/pdf/12906_2015_Article_762.pdf

Robert Kiss

Thank you so much Saleh!

This is very helpful!

Robert