Dear Colleagues, we all know that bacterial cell wall is negatively charged. Does any one know if the same thing is also apply to fungal cell wall ? best wishes, Amr Edris, National Research Center, Egypt
Hi, as both bacteria and fungi have cell wall. I presume fungi cell wall is mostly negatively-charged as well.
Yo may refer to the following links for more information:
1) Article Fungal cell wall phosphomannans facilitate the toxic activit...
2) Article Fungal Cell Wall Organization and Biosynthesis
Dear collegues,
No, the cell wall of fungi is not negatively charged.
Fungi have an outer cell wall, composed of polysaccharides such as mannan, β-glucan, and chitin.
This structures of cell wall do not have a pronounced negative charge and more closely resemble eukaryotic mammalian cells.
see:
https://www.researchgate.net/.../Cell-wall-structures-of-Gram-positive-and-Gram-negative bacteria and ......
Hi
Fungal have cell wall that is widely described.
The negative charge of fungal wall is due to mannoproteins that harbor phosphate groups.
Mohammad
Thanks Issawi for your contribution
I am confused in fact because another answer came from another colleague (see the answer of Marpha) wich indicated:
" Fungi have an outer cell wall, composed of polysaccharides such as mannan, β-glucan, and chitin. This structures of cell wall do not have a pronounced negative charge and more closely resemble eukaryotic mammalian cells.
So, what is the truth ??
Amr Edris
Mr. Chong is right.
Fungi cell wall is mostly composed of glucan-chitin complex and mannoproteins. Moreover, these mannoproteins are linked to beta-glucans via glycophosphate groups that contain 5 mannose residus. So the phosphorylated mannosyl side chains give fungal cell wall its negative charge.
See Lipke and Ovalle 1998. Cell Wall Architecture in Yeast: New structure and new challenges.
Mohammad
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