How to Make a Pre-Emulsion of Methacrylic acid, Butyl Acrylate, and Acrylonitrile to use in emulsion polymerization ?

Any answer will be useful / Surfactants / Procedure I am using this pre-emulsion in sequential emulsion polymerization

14 January 2021 2,566 4 View

What is iodine number in terms of activated carbon? What are the effect of iodine number on activate carbon porosity ?

11 March 2020 5,239 3 View

How to apply deep learning for estimation of various parameters in single carrier system?

Parameters like carrier frequency, symbol timing offset and symbol rate estimation in a single carrier system.

23 February 2020 2,980 4 View

Which circuit design should I use to generate emf oscillating at frequency of 2.5Ghz ?

I am looking for a circuit which can generate an emf oscillating at frequency of 2.5Ghz. My setup is in such a way that, I am passing particles (negligible mass) from a tunnel and want an emf...

21 December 2019 9,800 6 View

What can possibly replace Aluminium in Aerospace industry?

I am looking for material which can replace aluminium in aerospace industry as i want material which will be having high melting point and must be light in weight. As i am looking at this from...

20 May 2019 9,612 28 View

Activity of antibodies coated Gold Nanoparticles?

Hi Folks, I am developing a LFA for detection of a specific disease. I have functionalised the gold nanopartciles with polyclonal antibodies against bacterial surface proteins (The antibodies are...

01 June 2018 2,553 1 View

Is there any way we can compare the two sexes and make a statement that effect is more pronounced in one sex compared to other?

We have used both male and female mice for some behavioral analysis. Our 3-way ANOVA results show that some parameters are significant in one sex but not in other sex (compared to control in each...

02 March 2018 195 3 View

Why indian scientific researcher go abroad rather than doing best in india? beside so many things availiable why we can't innovate ?

Give suitable comments on personel experiences......

25 January 2018 1,985 11 View

Does any one have java code (program) of PCA for Data mining?

Does any one have java code (program) of PCA for Data mining?

01 January 2018 8,418 4 View

How to generate mesh as shown in image in Abaqus?

For indentation simulation mesh attached in the image is recommended. How can i generate this kind of mesh? I tried sectioning the solid and putting 'seed' but can't get the exact pattern. any...

23 October 2017 2,165 3 View

How to calculate Ligand-active site distance in a ligand-protein complex from MD simulation?

I have run a MD simulation of a ligand-protein complex in GROMACS using CHARMM forcefield. Reviewer has asked me to calculate Ligand-activesite distance and binding free energy of ligand with...

27 February 2021 4,703 1 View

What are the potential shell well and atomic solvation parameters for the boron atom?

I have a protein-ligand docking project. The ligand contains boron atoms that are not detected by Autodock software. To solve this problem, it is necessary to introduce the boron atom to...

19 February 2021 1,236 1 View

How long does it take to design and validate transition state analogue inhibitors?

Hi, I'm asking from the point of view of designing a research plan: How long (approximately) can it take to determine the transition state structure of an enzyme substrate using kinetic isotope...

14 February 2021 2,610 1 View

How to check if the PMF profile obtained from ABF simulation is correct?

I am doing ABF simulations to calculate ligand binding enegy. The PMF profile that I get using single long ABF simulation is attached as pmf_total.png. When I do this ABF calculation with 10...

10 February 2021 4,170 2 View

Ligands with 3,4,5-trihydroxyphenyl group?

Hi In the design of a bidentate ligand with imine group, is it okay to have a 3,4,5-trihydroxyphenyl group in the structure? In other words, does the 3,4,5-trihydroxyphenyl group compete with...

08 February 2021 4,977 7 View

How to Remove different version of atom from pdb Crystal Structure for Docking Preparation?

I am new to Docking and MD, and currently try to catch on it. I try one of the webserver for docking, but unfortunately not working. it says " Your PDB contains multiple forms of the same residue...

08 February 2021 7,426 3 View

Is there any difference between "SEP" as a non standard residue and phohophorylated serine?

I am trying to run a molecular dynamics simulation for a ligand that contains a "SEP" residue. also, I am preparing my files using Charmm-GUI using charmm36 ff, but it says that it will rename my...

31 January 2021 6,321 1 View

How do you get around this AutoDock Vina error?

I get the following error messages after running the simulation: Sorry, there are no Gasteiger parameters available for atom ligandx.ligand:A:lig1:O7 AutoDock Vina ligand docking initiated for...

26 January 2021 3,822 3 View

The dimensionality of protein and ligand is reduced after docking?

I used autodock to complete the docking between the ligand and the protein. I have a question, why the dimension of the result after docking is much smaller than the dimension of the protein...

24 January 2021 7,363 3 View

Best tool to build missing residues, minimize and validate a ligand model?

I am working on a ligand that is co-crystalized to parotein, but the ligand is missing some residues that makes it appear as if it was separated into two ligands! what I need is to connect them...

23 January 2021 3,975 7 View