The COPD is freqent. Parasitic-infestatio is even more and causes blood-eosinophilia. How can be predictiv the count of eo on COPD exacerbatio-phenotyp without exclusion of the helminthiosis or other parasitic disease?
Hi. Thanks. I think so, too. But why not? It is a essential problem by classification in COPD phenotyp and by treatment(see mepolizumab) eosinophilic severe asthma. Best regards Paula
This is an important question for initialization and possible interruption of anti IL5 therapy. Eosinophils play an important role in the immunological response to some helminth infections. Patients with pre-existing helminth infections should be treated before starting anti IL5 therapy. If patients become infected whilst receiving anti IL5 treatment and do not respond to anti-helminth treatment, temporary discontinuation of therapy should be considered. When choosing anti IL5 therapy, it is worth considering that they have different effects on eosinophils. These therapies reduce the number of cells in different level. My opinion is that a complete eosinophils eradication must be avoided.
on tbe other hands, the kids with parasites rarely have astma, or respiratory symptoms apart from Loêflër.
- Badges
- Science topic
- Similar topics
- Linguistics
- Composition Studies
- Publication