Does it act in a similar fashion to the function of netrin in axon guidance? For example, does it have a role in attracting axons of spinal commissural interneurons to the ventral midline, or does netrin have a distinct function on myeloid cells? Is there evidence of microglia homing to sites of netrin production in the developing nervous system, perhaps at the ventral floor plate? This is a fascinating paper and I would be grateful for additional insights.
Article Neuronal ER Stress Impedes Myeloid-Cell-Induced Vascular Reg...
John R Henley
I tried asking this question previously but appear to have been unsuccessful in getting it to post. Apologies in advance if this is a duplicate. I am enthusiastic about learning more on this topic.
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