I am looking at the relationship between hypertension and kidney disease/failure. It will also be advantageous to know the disease process of kidney disease/failure as a complication of hypertension.
High blood pressure increases the risk of developing kidney disease. High blood pressure can damage the kidneys. This reduces the kidneys' ability to remove fluids and waste products from the blood, and can lead to kidney failure.
Hypertension is a second cause of kidney disease and kidney failure.
One of the most common causes of hypertension is high fructose and carbohydrate intake. Fructose reduces NO production in several biochemical mechanisms, so blood pressure rises. The other effect of carbohydrates and fructose is to increase the level of inflammatory factors. (TNF alpha, IL-8, IL-6, etc.) The associated problem is that the kidney's medullary tissue uses glucose to produce ATP but cortex tissue ketone bodies. The average patient is unfortunately not producing ketones because he lives on carbohydrate. Therefore, after a while, neither cortex tissue nor medullary tissue can function physiologically. Renal failure is a metabolic action that can be quickly and efficiently improved with ketosis. But unfortunately, these patients are strictly prohibited from fat and meat, which is dangerous to further the problem. That is hypertension and renal failure, both of which are consequences. Hypertension is not a cause of renal failure, but a parallel phenomenon due to one reason. Increase intake in Carbohydrate and Fructose - elevated Inflammatory Factors - metabolic disturbance in the tissue - tissue and organ failure
Hypertension is one of the leading cause of CKD & hypertension is also a common complication of CKD , leading to worsening of CKD . It is difficult to identify which came first ! The articles by Sergey Kozhukhov & Adam B Shapiro explain the mechanisms of hypertension & CKD.
This is a well established correlation, hypertension is a leading cause of CKD and most of renal disorders can presented by hypertension . {secondary cause of hypertension}.