An approximately 40 yo male with a non-healing wound on lower leg infected with M. chelonae that shows resistance to clarithromycin. Looking for an alternative course of treatment.
Atypical mycobacterial infections, like tuberculosis, usually need multidrug therapy. Clarithromycin, in combination with other antibiotics, is a first line drug for sucn infections. However, in cases of clarithromycin ressistance, a combination of doxycline/minocycline , a quinolone (cipro/ofloxacin), and co-trimoxazole may be tried..
Thank you for your answers. What would be the best course of treatment? With clarithromycin, I have seen case studies that continued treatment up to 6 months after the patient showed signs of response.