The first signs of reinnervation of the Pacinian corpuscles have been established at the middle of the second month after nerve crush.
I am not sure what you mean by neuroregeneration of ACL grafts. To the best of my knowledge the ACL does not have any nerves within its structure. Please explain.
We believe that the ligament's function is both mechanical and
neurological. Through gold chloride staining and immunohistochemical
studies, we have found, as have others using different techniques,
mechanoreceptors in the body of the canine ligament (see refs below).
Surprisingly these receptors were mostly in the body of the ligament
not at the attachment sites.
The mechanoreceptors probably play a protective role, since mechanically
speaking, ligaments have a low security factor compared to bone. The
security factor of the ligament is of the order of 1 compared to the
bone's security factor which is of the order of 4 to 6.
Mechanoreceptors in the canine anterior cruciate ligaments.
L H Yahia, N Newman .
Anatomischer Anzeiger 02/1991; 173(4):233-8. pp.233-8
Yahia L.H., Newman N. St-Georges M."Innervation of the Canine Cruciate
Ligaments", Anat. Histol. Embryol., 21:1-8, 1992.
see also : Journal ofBodyworkandMovementTherapies(2009) 13, 136–154
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