Does anyone know of a method to measure enoxacin in plasma?

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Michael A. Eldon

You can find the HPLC method that we developed at Parke-Davis and used for the clinical development of enoxacin in this article:

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, May 1989, p. 615-617

AAC is open source so the full text can be easily downloaded.

Iddo Magen

Thanks Michael.

Do you know whether this method is routinely used, by Parke-Davis or other companies including yours?

Iddo

It was used by Parke-Davis during for the clinical development of enoxacin in the late 80's/early 90's. It cannot be in use by Parke-Davis today because the company was acquired by Pfizer and thus no longer exits.

My current company has never worked with enoxacin.