Are there any lipid transport proteins that actively transport phospholipids (mainly phosphatidylcholine) into the lipid bilayer they are stuck in?
I am looking for a protein that transports PC in one direction, not in both directions by simple diffusion, and that has as small a molecular weight as possible.
I feel that such a protein might exist in an obligate intracellular parasite that cannot synthesize its own phospholipids, but I have not yet been able to find any literature indicating such a thing.
I appreciate the response.
Thank you for your answer.
I am looking for membrane proteins that transfer phospholipids from other lipid bilayers to the lipid bilayer in which they are embedded, rather than flippases that transfer phospholipids within one membrane. I have been able to find some soluble proteins (such as StarD7) that move PC in both directions, and I already know of one(ABCA1) that transfers phospholipids and cholesterol from the lipid bilayer in which it is embedded to another(ApoA1). However, I could not found the protein I want.
This may be useful:
Article Architectures of Lipid Transport Systems for the Bacterial O...
You may find something useful here:
https://rupress.org/jcb/article/220/3/e202012058/211813/Mechanisms-of-nonvesicular-lipid
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