Does anyone know a technique to determine the encapsulation efficiency of curcumin in solid lipid nanoparticles?

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Sofia A Papadimitriou

Maybe you could try with indirect method.Measure the amount that was not entrapped on the supernatant.

Zoraida P Aguilar

Here is a reference where there is a description of how they measured the curcumin-lipid NP encapsulation efficiency. You can adopt their process for your research: http://www.sciencedirect.com/science/article/pii/S0927776513004086