Does anyone know a technique to determine the encapsulation efficiency of curcumin in solid lipid nanoparticles?

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Sofia A Papadimitriou

Maybe you could try with indirect method.Measure the amount that was not entrapped on the supernatant.

Darsheen Kotak

Yes, Go through indirect method. From that you will get the idea.

Zoraida P Aguilar

Here is a reference where there is a description of how they measured the curcumin-lipid NP encapsulation efficiency. You can adopt their process for your research: http://www.sciencedirect.com/science/article/pii/S0927776513004086