I was wondering if anyone had a good reference(s) for aerosol inoculation of viruses in mice. I am interested in any information people can recommend.
I was also wondering if anyone has experience using the DSI Buxco inhalation tower for viral infections. If so, what is your a opinion of the deliver system?
Thanks in advance!
Bowen, LE, K Rivers, JE Trombley, JK Bohannon, SX Li, JA Boydston and MC Eichelberger (2012). Development of a murine nose-only inhalation model of influenza: comparison of disease caused by instilled and inhaled A/PR/8/34. Front Cell Infect Microbiol 2: 74.
Gustin, KM, JA Belser, JM Katz, TM Tumpey and TR Maines (2012). Innovations in modeling influenza virus infections in the laboratory. Trends Microbiol 20(6): 275-81.
McDonald, RS, AR Sambol, BK Heimbuch, TL Brown, SH Hinrichs and JD Wander (2012). Proportional mouse model for aerosol infection by influenza. J Appl Microbiol 113(4): 767-78.
Rivers, K, LE Bowen, J Gao, K Yang, JE Trombley, JK Bohannon and MC Eichelberger (2013). Comparison of the effectiveness of antibody and cell-mediated immunity against inhaled and instilled influenza virus challenge. Virol J 10(1): 198.
Smith, JH, T Nagy, J Barber, P Brooks, SM Tompkins and RA Tripp (2011). Aerosol inoculation with a sub-lethal influenza virus leads to exacerbated morbidity and pulmonary disease pathogenesis. Viral Immunol 24(2): 131-42.
Thomas, RJ, D Webber, W Sellors, A Collinge, A Frost, AJ Stagg, SC Bailey, PN Jayasekera, RR Taylor, S Eley and RW Titball (2008). Characterization and deposition of respirable large- and small-particle bioaerosols. Appl Environ Microbiol 74(20): 6437-43.
Ralph Tripp's group has done some work with the aerosol inoculation of mice
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066694/
Bowen, LE, K Rivers, JE Trombley, JK Bohannon, SX Li, JA Boydston and MC Eichelberger (2012). Development of a murine nose-only inhalation model of influenza: comparison of disease caused by instilled and inhaled A/PR/8/34. Front Cell Infect Microbiol 2: 74.
Gustin, KM, JA Belser, JM Katz, TM Tumpey and TR Maines (2012). Innovations in modeling influenza virus infections in the laboratory. Trends Microbiol 20(6): 275-81.
McDonald, RS, AR Sambol, BK Heimbuch, TL Brown, SH Hinrichs and JD Wander (2012). Proportional mouse model for aerosol infection by influenza. J Appl Microbiol 113(4): 767-78.
Rivers, K, LE Bowen, J Gao, K Yang, JE Trombley, JK Bohannon and MC Eichelberger (2013). Comparison of the effectiveness of antibody and cell-mediated immunity against inhaled and instilled influenza virus challenge. Virol J 10(1): 198.
Smith, JH, T Nagy, J Barber, P Brooks, SM Tompkins and RA Tripp (2011). Aerosol inoculation with a sub-lethal influenza virus leads to exacerbated morbidity and pulmonary disease pathogenesis. Viral Immunol 24(2): 131-42.
Thomas, RJ, D Webber, W Sellors, A Collinge, A Frost, AJ Stagg, SC Bailey, PN Jayasekera, RR Taylor, S Eley and RW Titball (2008). Characterization and deposition of respirable large- and small-particle bioaerosols. Appl Environ Microbiol 74(20): 6437-43.
poultry vaccine companys use this kind of technic. you can search on the company site. some of them uses films for information. (youtube)
Tellier, R (2006) Review of Aerosol Transmission of Influenza A Virus. Emerging Infectious Diseases, 12(11), 1657-1662. http://wwwnc.cdc.gov/eid/article/12/11/06-0426_article
Herfst, S, Chutinimitkul, S, Ye, J, de Wit, E, Munster, V.J, Eefje J. A. Schrauwen,1 Bestebroer,T,M., Jonges, M, Meijer, A, Koopmans, M, Rimmelzwaan, G.F, Osterhaus, A. D. M. E, Perez, D.R & Fouchier, R.A.M. (2010). Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission. Journal of Virology, 84(8), 3752-3758.
http://jvi.asm.org/content/84/8/3752.full.pdf+html
Hostetler, K.Y. (2010). Synthesis and Early Development of Hexadecyloxypropylcidofovir: An Oral Antipoxvirus Nucleoside Phosphonate. Viruses , 2, 2213-2225;. doi:10.3390/v2102213
Shannon, S.M., Bakken, R.R, Lind, C.M, Garcia, P, Jenkins, Glass, P.J, Parker, M.D,Hart, M. & Fine, D.L. (2010). Evaluation of formalin inactivated V3526 virus with adjuvant as a next generation vaccine candidate for Venezuelan equine encephalitis virus, Shannon S. Martin. Vaccine. 2010 April 19; 28(18): 3143–3151. doi:10.1016/j.vaccine.2010.02.056. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857980/
Medina, R.A, Manicissamy, B., Stertz, S, Stilbert, CW, Hai, R, Belshe, RB., Frey, SE, Basler, CF, Palese, P & Garcia-Sastre, A. (2010). Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature,1(28), 1-6. http://www.nature.com/ncomms/journal/v1/n3/full/ncomms1026.html
White, AD, Sibley, L, Dennis, MJ, Gooch, K, Betts, G, Edwards, N, Reyes-Sandoval, A, Carroll, MW, Williams, A, Marsh, PD, Sharpe, SA. (2013). Evaluation of the Safety and Immunogenicity of a Candidate Tuberculosis Vaccine, MVA85A, Delivered by Aerosol to the Lungs. Clinial and Vaccine Immunology, 20(5), 663-667. http://cvi.asm.org/content/20/5/663.full
Recommend the directed flow radial inhalation exposure system from In-Tox Products, LLC. No shared atmosphere.
www.intoxproducts.com
http://journal.frontiersin.org/article/10.3389/fcimb.2012.00074/full
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691648/