Does anyone have good comments about Cell tracking with nanoparticles or radiolabeling the cells?
Thanks Esra,
what a bout combination of two methods such as SPECT/MRI?
http://www.researchgate.net/publication/236979640_Evaluating_the_Effect_of_Uspio_Nanoparticles_for_21_Days_Post_Magnetic_Cell_Labeling/file/e0b4951a9cd1c96a71.pdf
Article Evaluating the effect of ultrasmall superparamagnetic iron o...
Chapter Evaluating the Effect of Uspio Nanoparticles for 21 Days Pos...
Dear Saeed, there are some works in which are combined SPECT and MRI. For example you have:
Magnetically decorated multiwalled carbon nanotubes as dual mri and spect contrast agents. Advanced Functional Materials. 2014. 24 (13), pp. 1880-1894
Best regards
Most of these works are just for fun (or funding) and publications, but not clinically applicable, I am afraid.
In-111 oxine and Tc-99m HMPAO are two radiopharmaceuticals that are used clinically to tag white blood cells ex-vivo for reinjection into patients. There are commercial cell membrane intercalating dyes that can be used for optical imaging. There are numerous radiolabeled cell membrane intercalating dyes and phospholipid analogs that also can tag cells. All of these methods have pros and cons which will depend on your particular application.
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