Are there any explanation or report on sub-cellular localization of negatively charged molecules (drug) on mitochondria? Please help me with mechanism and explanation.
Dear Sabarinathan Rangasamy ,
Check these out:
Drug Des Devel Ther. 2013; 7: 585–599.
Organelle targeting: third level of drug targeting
Niraj M Sakhrani and Harish Padh
Potential Therapeutic Benefits of Strategies Directed to Mitochondria
Amadou K.S. Camara, Edward J. Lesnefsky, David F. Stowe
Antioxid Redox Signal. 2010 August 1; 13(3): 279–347
Mol Aspects Med. Feb 2010; 31(1): 75–92.
Published online Dec 6, 2009. Small mitochondria-targeting molecules as anti-cancer agents
Feng Wang, et al.
Mitochondrion Volume 3, Issue 4, March 2004, Pages 229–244
Mitochondrial pharmaceutics
Volkmar Weissig, Shing-Ming Cheng, Gerard G.M D'Souza
Murphy MP, Smith RA. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv Drug Deliv Rev. 2000;41(2):235–250.
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