It is understood that bacteria are resistant to its own antibiotics. I carried out the antibiotic resistance profile of the antibiotic producer bacterial isolates. The Isolates were resistant to different classes of antibiotics. So i assumes the bacteria might produce the same class of antibiotic to which it was resistant. I need suggestion.
You cannot make that assumption. Yes a bacteria will be resistant to its own antibiotic however, production of the antibiotic is not a prerequisite to resistance. For example all gram negative species are resistant to penicillin, that does not then mean that all gram negatives produce penicillin.
I would look into the mode of action of the antibiotic you are studying to see what method of resistance may be occurring.
I totally agree with Dr. James as antibiotic production could not be assumed as such.
You must have to take into consideration that there are a number of different mechanisms of resistence against antibiotics: their destruction inside the bacterial cell and their excretion by transport proteins (more or less specific extrusion pumps)
Hi, antibiotic resistance in bacteria is not usually associated with the antibiotic production. For example some bacteria have natural resistance to an antibiotic (or a class of antibiotics) because they lose the target, like resistance of Mycoplasma to B-lactam antibiotics due to lack of cell wall (peptidoglycan).
Please, take also into account that a lot of antibiotics is being produced by fungi but highly limited to only several classes/groups of bacteria whilst nearly all bacterial taxa have developed (or received by horizontal gene transfer, plasmids, transposons, ...) such traits.
This clearly answers your question: those (your bacteria included) may produce antibiotics, are - logically spoken - resistant against those, and may be - additionally - resistant against may other classes of antibiotics, or even not at all.
I don't think that antibiotic resistance in bacteria gives any clue about antibiotic production .
Ranveer Singh,
Please give any reasons for your reply to the above question; the opinion of people or what they think is of little help for those who need an answer which helps them. Sorry for this comment.
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