do you have any experience with pulmonary blastoma in a young female obstructing the right main bronchus and reaching the carina ?
Treatment of PB is very difficult. Prognosis in this type of cancer is really poor. The majority of cases occur in the right hemithorax. Because most of these tumors are located peripherally, resection is usually possible by segmental or lobar resection. The use of multimodal neoadjuvant chemotherapy and radiation following surgical resection has shown promising results in a few patients with extensive disease and dissemination. 41, 75 Chemotherapeutic agents that have been used include actinomycin D, vincristine, cyclophosphamide alternating with courses of doxorubicin, and cisplatin. Histologic evaluation of the tumor shows an exclusive mesenchymal composition, including primitive tubules, immature blastema, and spindle cell stroma. Fairly rare occurrence but this may help with a starting point.
Pulmonary Blastoma
.AnooshiravanNazariM.D., F.C.C.P.. .EbrahimAmir-MokriM.D.. .AbbasSarramM.D.. IssaYaghmaiM.D.
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https://doi.org/10.1378/chest.60.2.187
Pulmonary blastoma is a rare and potentially malignant tumor capable of metastasis. To date, there have been 15 cases reported in the literature. This report describes the histogenesis of this type tumor and discusses other rare pulmonary neoplasms..