Since ancient times over thousands of years until modern technological era human diet and drinks were simple devoid of chemical food additives.. With the advent of Modern technological era human drinks and diet are supplemented with various substances. Over 3000 chemicals or others are added as food supplements to prevent decay and please the eye. Food preservatives and other substances have tremendous influence on the microbiome of human intestine. Endotoxins produced by the microbial flora may result in endotoximia. This may be responsible for many diseases and maladies in man.
There are several comments needed as this question begins to get answers.
First, the lack of a variety of fibers in the modern diet is a large part of the problems for the microbiome. These prebiotics are needed for proper health of our microorganisms.
Second, while the historic diet was much more whole food and many less additives, we should not forget that salts and sugars were routinely used as part of food preservation for many centuries.
Third, while a lot of LPS (the chemical that causes endotoxic effects) is in the intestinal lumen, it appears little seems to be absorbed into the blood in healthy individuals. Possibly the dysbiosis of the other additives or overgrowth of some bacteria may cause a greater leaking of LPS out of the intestinal lumen.
Please have a look at this useful RG link.
Article The Impact of Diet and Lifestyle on Gut Microbiota and Human Health
Please also take a look at the following RG links.
Article Influence of diet on the gut microbiome and implications for...
Article Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration
Article The Gastrointestinal Microbiome: Alcohol Effects on the Comp...
Please also go through the following RG link.
Article Differential effects of whisky brands on human gut microbiom...
- Badges
- Science topic
- Similar topics
- Linguistics
- Composition Studies
- Writing