What are some good examples of articles for moderately polar compounds separated by HILIC?

LogP

20 September 2017 5,023 4 View

Are there any infra red detectors for HPLC or UV+IR detector for liquid or gas or supercritical fluid chromatography?

Just wondering about their expense to make. Does liquid propulsion cause excess interference in IR?. A multifunctional HPLC that checks for impurities would be more valuable. Does the liquid...

07 September 2017 3,555 4 View

How to dissolve acidic peptide?

Hi all, I know there have been questions and answers on how to dissolve an acidic peptide. However, my questions will be: a) Can I dissolve my peptide using a basic solvent such as NaOH instead of...

02 September 2017 4,042 5 View

Phenazines and pyocyanin contain a chromophore. What makes it contain a chromophore in its structure?

I know benzene rings in tryptophan at 280nm give the absorption so is this the only criterion for a molecule to possess a chromophore?. Or do the functional groups play a pivotal role along with...

29 August 2017 3,081 5 View

How efficient in plate count are gaurd columns on their own such as C18 based gaurd column or one of a different material such as ion exchange/ HILIC?

"A properly designed guard column does not deteriorate the separation. As a matter of fact, a well designed and well packed guard column using the same material as in the analytical column is a...

26 August 2017 6,915 12 View

What is the sensitivity of hplc uv DAD detector compared the the BDD electrode?

The Boron doped diamond electrode is very sensitive. I need to know how hplc uv DAD compares so that I can perform easy Limit of detection testing without making up too many samples, and even...

26 August 2017 185 4 View

What statistical method do I use to calculate HPLC resolution?

25 August 2017 1,613 4 View

Is pyocyanin an alkaloid and/ or a phenazine compound and is pyocyanin secreted by plants or similar compounds?.

I do not understand if pyocyanin is a betaine compound (alkaloid group family being zwitterionic at neutral state) then how is it also a phenazine compound?. Is pyocyanin secreted by plants that...

12 August 2017 1,140 2 View

Which phenazines are polar and nonpolar?

04 August 2017 6,252 1 View

Are there any research papers on Pseudomonas aeruginosa time taken for biofilm formation?

Along with which virulence factors produced during that biofilm transition stage from the planktonic cells. Its good that it was found that cells experience shear stress and flow for formation of...

04 August 2017 9,243 4 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Which is the best place in the world for the plant biotechnology research?

I am searching for a good place for the Post Doc,

02 March 2021 4,053 3 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Which bacteria are suitable for quorum sensing screening?

I want to find a quorum sensing inhibitor from plant extracts. Klebsiella pneumoniae, Moraxella catarrhalis, Staphylococcus aureus, and Streptococcus pneumoniae. I looked for these strains...

01 March 2021 7,675 3 View

Isolates of Hymenoscyphus fraxineus?

Dear Dr. Cai, my name is Simone Prospero and I work in the team of Phytopathology at the Swiss Federal Institute for Forest Snow and Landscape Research (WSL;...

01 March 2021 1,133 1 View

How to remove the residual PDMS on the silicon mold?

Incompletely cross-linked pdms are difficult to remove.

01 March 2021 798 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View