Difference between bacterial derived vs host-derived extracellular vesicles?

30 July 2024 0 3K Report

I am infecting phagocytic or non-phagocytic cells with bacteria and isolating the extracellular vesicles (which may contain both exosomes or microvesicles). I performed the TEM imaging of the isolated extracellular vesicles (attached below). However, I am confused about whether this is bacterial-derived, which they shed as outer membrane vesicles OR host-derived. Is there a way to differentiate by morphology?

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