Liposomes prepared by non-mechanical methods have disadvantages such as poor uniformity, poor reproducibility, and large particle size the prepared liposomes. Therefore, some mechanical methods are often used to obtain uniform and stable liposomes.

Common mechanical methods include Extrusion, Ultrasonication disperse, high-pressure homogenization, Dynamic high-pressure microfluidization, DHPM.

You can also find a professional liposome company to help you solve all your problems. Details can be accessed at https://liposomes.bocchem.org/

Hi Moustafa,

How did you evaporate organic solvent from double emulsion? I tried nitrogen gas purging and rotary evaporation, both methods are leading to emulsion cracking. Is there any way to optimise this? which instruments did you use to prepare double emulsion? Your help will be greatly appreciated. Thank you.