How do we calculate the loading dose and maintenance dose in development of SR multiple unit pellets (Coated) ?

In some disease conditions the there is lag time to achieve the PDC in the therapeutic range. Therefore, there is need to administered loading dose separately or together with maintenance dose.

02 March 2019 1,104 1 View

Pelletization and pellet coating is/being explored to satisfy the need of Loading dose and maintenance dose concept ?

Loading dose and maintenance dose concept

11 December 2018 7,861 0 View

What is the fate of large Mol. Wt. drugs that are administered in parenterals ?

Development of parenteral formulation of large Mol. Wt. (More than 800 Dalten substance.

10 November 2018 9,092 1 View

What are the challenges for developing protein and peptide drug delivery?

Protein & Peptide Drug Delivery

10 November 2018 5,349 3 View

Is intra muscular parenterals are suitable for large mol. Weight drugs about 850 Dalten ?

Intra muscular or depot preparation s

10 November 2018 3,821 0 View

Are the carbon tubes a better approach for cancer drug targeting ?

In relation to active drug targeting

06 July 2018 10,020 0 View

What is maximum amount of residual solvent allowed in oral and /or parenteral formulation

05 June 2017 2,616 0 View

Computer Aided Drug Delivery

Reference book or Journal etc

01 January 1970 7,961 3 View

In vitro modelling for renal cell cancer

Cell toxicity study

01 January 1970 8,835 1 View

Polymer composites suddenly solidifies?

I am making polymer composite by solvent mixing method. When I am trying to add filler solution in polymer solution it quickly get solidified. How to make them then uinform? It doesn't give time...

03 March 2021 7,540 4 View

Chlorinated organic formation in odor control scrubbers using hypochlorite?

I'm involved in a study of odor control technologies for municipal wastewater treatment plant. One of the control options involves a chemical 2-stage (acid/alkaline) packed bed scrubber. The...

03 March 2021 3,661 2 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

How the parameters (such as Mw, Chemical bonds, polymer bland and so on) affect the mechanic property of polymer (such as storage, loss modulus) ?

Anyone can recommend any books on such topics? Thanks in advance.

02 March 2021 8,457 2 View

How do I determine the degree of polymerization of PEG 400 based on NMR integration?

Hello, I am working on the photocatalytic degradation of PEG 400. I would like to know if it's possible to determine the degree on polymerization based on NMR integration, or by the MW of the...

02 March 2021 6,186 3 View

How to polymerize TEOS?

I want to polymerize TEOS on a surface. I know that NH4OH is a preferred catalyst and an alcoholic solvent should be used .But I can not find certain amounts of each material to use. Does any one...

02 March 2021 1,404 6 View

Which is a lucid standard comprehensive book to guide on psychological scale construction and its standardization?

02 March 2021 7,082 3 View

Ester cleavage conditions?

Hi all, I need to cleave the ester in Ethyl 2-amino-1H-imidazole-5-carboxylate to make the carboxylic acid and retrieve the product from solution to use in downstream applications of linking to...

01 March 2021 8,766 3 View

How can extract ciprofloxacin hydrochloride disolve in water er to organic solvent such as dichloromethan or any other solvent?

I need a procedure to extract the ciprofloxacin hydrochloride from aqueous solution by using dichloromethane in detail,. I thank you very much.

01 March 2021 4,306 1 View