Could you suggest, some companies which can provide customized tetramer synthesis MHC class-II Antigen?

29 December 2021 0 6K Report

I am looking for customized tetramer synthesis for HLA DQ epitopes (MHC class-II), so could you please suggest sources please.

Badges
Science method

More Sambuddha Kumar's questions See All

Do you think can be any Uranium bearing rocks in Eastern part of Iran and western part of Afghanistan?

I want to know more about Uranium ore deposits in world.

11 August 2024 6,718 0 View

Do you think can be any diamond bearing rocks in Eastern part of Iran and western part of Afghanistan?

I want to know more about diamond ore deposits in world.

11 August 2024 2,166 1 View

If Banks do not provide credit facility, what are the options available for FPOs and impact on producer’s income?

10 August 2024 8,197 5 View

What is the difference between mathematical R^4 space and physical 4D unit space?

We assume that the difference is huge and that it is not possible to compare the two spaces. The R^4 mathematical space considers time as an external controller and the space itself is immobile in...

10 August 2024 6,676 14 View

What are a “Farmers Producer Organization” (FPO) and its essential features?

10 August 2024 475 5 View

Controlling for pupil light reflex when analyzing pupil size time course?

I used eye tracking to examine how participants from two different populations (A and B) react to an image. Participants in population A exhibit larger pupil sizes over time, but they also have...

10 August 2024 3,226 0 View

Strugglling with m6A dot blot any suugesstion ?

I have been doing the m6A dot blot for a while with no improvement, I am extracting the RNA, and I can see the dots although the three biological replicas give a different reading on the memberan...

10 August 2024 8,537 5 View

Do interactions between biosphere, carbon cycle, & water cycle impact global warming & interaction between atmosphere & hydrosphere?

How do interactions between the biosphere, the carbon cycle, and the water cycle impact global warming and interaction between the atmosphere and the hydrosphere?

09 August 2024 3,286 2 View

How to get moment output in Abaqus Standart?

I have input a moment load in module load Abaqus, i put my moment load on the node surface (using reference point). I have define moment in history output and make a set for moment too. But the...

08 August 2024 4,829 4 View

How is energy cycled through the Earth's climate system and how do matter cycle and energy flow through the rock cycle?

08 August 2024 8,159 0 View

Population coverage analysis for some MHC II alleles?

Hello everyone Does anyone know how could we determine population coverage of some MHC II alleles such as HLA-DRB3*02:02, HLA-DRB5*0101, HLA-DPA1*02:01-DPB1*05:01, HLA-DRB4*01:01,...

20 June 2024 2,154 1 View

Can CD45+ Mesenchymal Stem Cells Exist?

Hello everyone. I performed immunofluorescence staining to characterize MSCs that I isolated from the placenta. As expected, the results were CD90+, MHC-, and SOX2+. However, CD45, which should be...

28 February 2024 4,314 3 View

Is it possible to republish an already published article by chancing the used appellations into currently new defined scientific terminologies?

I already published an experimental research paper entitled "Neuroanthropology: Olfactory Recognition of the Self / Non-self by the Ancestral MHC: An EEG Study" in 2012 (doi:10.5539/ijb.v4n4p1)....

07 January 2024 2,508 4 View

Can I merge T cell from two different host?

My lab co-worker need a lot of T cell for his animal experiment, however one of the donor can't provide enough for downstream analyses, we thought to combine purified T cells from two donors in...

06 November 2023 7,187 0 View

Tetramer - binding affinity?

Why is tetramer only used to test the interaction between T cell and peptide-MHC complex and not to test binding affinity between peptide and MHC?

12 May 2023 6,067 2 View

Why does antibody against MHC class I loaded with SIINFEKL localize in lysosomes, even without permeabilization in immunofluorescent staining?

I used an antibody against H2-Kb SIINFEKL tagged with APC on Dendritic cells treated with nanocarriers carrying SIINFEKL peptide. After 3 hour incubation, the cells were washed 3 times with PBS...

10 February 2023 6,785 1 View

Does the expression level of MHCII protein depend on the copy the alleles?

Hi. I have a question of the MHCII expression in mammal. What I know so far is that the expression of MHCII is codominant, alleles from both mom and dad will be expressed. However, I would like to...

25 July 2022 2,803 2 View

What will be the best way to choose MHC II epitopes and peptides?

By using IEDB server

31 May 2022 8,478 0 View

Blocking OTI - SIINFEKL MHC I mediated interactions?

Hello! I have a anti-mouse MHC Class I antibody (anti-H2Kb-H-2Db) that we are trying to prove works in blocking MHC I mediated interactions. We are using SIINFEKL and OTI mice as a model to do...

28 March 2022 2,339 0 View

Hi Everyone! I am designing a Dengue vaccine computationally and need help with how should I perform molecular docking of proteins and epitopes?

I have taken B cell epitopes from consensus protein and overlapping T cell epitopes from B Cell epitopes having MHC class I and II binders. Is is enough if I just dock B cell epitopes with protein...

22 March 2022 4,499 5 View