Continuation of retroviral RNA integration into the Human Genome.

03 March 2012 1 3K Report

Endogenous Retroviruses (ERVs) have been described as occurring in surprisingly large numbers in the human genome (up to 8%).

I have read reviews describing the proliferation of these once-RNA sequences as relating to their relative inactivity allowing them to survive the germ cell proliferation without being detected and eradicated during the endogenous ‘proof-reading' phase.

Is it possible that retroviral RNA sequences are still being integrated into human genomes as part of the explanation behind the extent of ERV section, so that some of these ERVs stem from contemporary integration of RNA, rather than ancient sources?

Gaurab Banerjee

A really interesting area. It would be great to learn more.

Eagerly awaiting some interesting facts and comments about the same. Please send me if you have any papers at [email protected].

regards,

Gaurab

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