Does some gene mutation that increase migration necessarily increase invasion?Is it possible that some mutation that enhance cell migration but inhibit its invasion?
Migration is a prerequisite for invasion. Non malignant cells can migrate without being invasive e.g. neutrophiles. Invasion requires the ability of digesting sorrounding tissues. This requires the activation of metalloproteases and other proteolytic enzymes. In turn this requires an acidic extracellular matrix. As you can see, everything is interrelated.
Migration can occur without invasion. The contrary is not possible.