Can you refer me to a comparison between olefinic metathesis and Click Chemistry and their adoption in peptides and peptidomimetics?

03 March 2013 0 4K Report

For example: reasons to prefer one method over the other? The relative-stability of the product? And the outcome conformational change in each?

Badges
Science topic

More Ashraf H. Abadi's questions See All

Is there a free software for biological/pharmacological activity prediction?

Would you kindly recommend a free online software that predicts the biological/pharmacological activity of small organic molecules from its structure? PASS is not working

08 September 2018 9,798 3 View

Collaboration on the discovery of phosphodiesterase inshiniors?

Dear All We are a research group situated in Cairo, Egypt, specialized in pharmaceutical research in topics pertaining to the discovery of Phosphodiesterase enzyme isoforms inhibitors .We are...

04 May 2018 8,203 2 View

Is there a microbiologist interested in testing potential anti HCV in replicon assays and sharing the outcome publications or patents?

We are synthesizing small organic molecules as potential NS5A inhibitors. we are looking for partners for testing in replicon assays against different genotypes in Huh-7. We need to determine...

10 November 2015 6,628 3 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View

Formulation of polymer color flakes

I am writing to request some information for making polymer color flakes. I would appreciate the help.

17 March 2021 0 0 View

Why does blocking with my immunogenic peptide cause nuclear fluorescence in ICC?

Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...

03 March 2021 5,999 3 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View