Title Systematic analysis of TRPM8’s polymorphism and the prediction of its association with diseases Abstract TRPM8, Transient Receptor Potential Cation Channel Subfamily M Member 8, is a protein-coding gene located on the second chromosome, and one member of the biggest subfamily of the transient receptor potential channel. TRPM8 is known for its ability to sense cold temperature or other cooling agents at the body level, including menthol, icilin, cold temperature. At the cellular level, TRPM8 is the non-selective cation channel that can control the movement of calcium ions flowing in or out of the cell. There has been enough research investigating TRPM8’s function as a sensitive temperature receptor, but seldom research has examined its polymorphism and amino acids change.
Thanks, can you send me your email address please so i can send you a formal request via scholastica? You will have 7 days too turn in your review. Much appreciated. I await your email.
Best,
Shireesh Apte
Thanks for invitation, but this topic is out of my field of research.
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