If a metabolic derangement is related with hypertension but not with pre-hypertension according to cross sectional studies, can we say that this metabolic abnormality is not the cause but the result of hypertension?
for example, high levels of X is associated with hypertension, but in prehypertensive patients level of X is normal.
every metabolic disfunction or abnormality is essentially due to disbalance or short of harmonal level which is also results from hypertension. As hypertension causes disturbances in level of dopamine and serotonin harmones
Actually the answer is "can we?". Because the definition of the metabolic abnormality is missing in the question. So what kind of metabilic abnormality that we discuss?
Lets say fatty liver. my question is if we look from the philosophic point of view..
I agree with Dr Avenatti. I was struggling to find my words but here they are.
I agree with Ms. Avenatti and Mr. Boudes. A cross-sectional study cannot establish temporality. In your case, metabolic derangements are associated with hypertension. But you never know which came first. There are different definitions of metabolic syndrome. One of them is having 3 of the five following components - 1) obesity 2) diabetes 3) hypertension 4) low HDL and high triglycerides. As long as you do not perform a cohort study (where people has other components but not hypertension) you never know whether other components of metabolic syndrome were present in a person before the onset of hypertension and vice versa. I shall suggest to be careful before interpreting this result.
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