In theory yes

because you can perform a 2 phases refinement with the same powder data for example

so it's in your editor of pcr file

you can read read the manual and the tutorials :

http://www.ill.eu/sites/fullprof/php/tutorials.html

And in practice NO !!!

@Tapabrata, it's not so easy to enter the information manually into the pcr file when you're refining for intermetallic phases, whose crystal structures are often defined by many tens of atomic sites.

The "CIF --> PCR" button in the EdPCR window of FullProf works beautifully to get CIF data for a single phase into a pcr. I just tried for a complicated intermetallic crystal structure and it worked beautifully. However, I was unable to do so to add a second phase into the same pcr file this way. So I just got around it by using this "CIF ->> PCR" feature separately for each phase and saving each as a separate pcr file, and then combining them on my own in MS Notepad (or other text editor) when I start to refine for the second phase. Hope that helps

In my practice, using Topas XRD refinement sofaware ,it can be viable .Two phase refinement is workable.

Yes, the original question does not ask about intermetallics specifically, but these have the most complicated crystal structures, many times defined by tens of atomic sites. Since the import feature I mention works for such complex structures, my point is that it should work for simpler structures. And with a few extra mouse clicks, the procedure can be repeated for every phase you want to refine. Clearly, the questioner faced the same problem as me and I just shared what solution worked for me.