Is it possible to couple the flash chromatography with HPLC or mass spectrometry, what should be the criteria for it and are are the challenges in it.
YES. Many companies provide this instruments.
http://yamazenusa.com/products/smart-flash-ms-system/
Isolera™ Dalton.... http://www.biotage.com/news/biotage-releases-fully-integrated-mass-directed-flash-system
etc..........
thank you sir
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