Yes

Recent work is to combine mixs of antibiotics and natural agents as plant extracts or modified proteins. Mostly, they act in synergism which give more antibacterial activity in different mechanisms.

Très bonne question. Je te recommande d'utiliser des cocktails qui peuvent être complémentaires et ainsi vous complexifier la composition et qui sera dure et rendra l'apparition de résistance Très peu probable.

Merci

Thank you, Gamal Enan

Dear Djahoudi Abdelghani ,

Thank you for your reply, kindly translate the sentence to English

translate of my french answer : Very good question. I recommend that you use cocktails which can be complementary and thus make the composition more complex for you and which will be hard and make the appearance of resistance Very unlikely.

Thank you, Djahoudi Abdelghani

Yes for sure, if the oils are missible or soluble (dissolvable)in the same volatile solvent (or solvent system) to be loaded further onto paper discs and assayed by adopting any reliable paper disc assay method.

This is usually done in case of studies about the synergy between different plant or algal extracts to reveal the potentiation effects of such extracts in mixed ratios to suppress or stop the microbial and/or fungal growth by MIC and MBC determination.

Thank you, Nabil Saleh

Yes it can be. Combinations are highly sought after. Using appropriate controls in all experiments, for the MICs and MBC also.

But, why combine the 'oil' which did not have any effect on pathogens with other oil? Can synergistic effect cannot be expected here, I think..

of course you can, keeping in mind this mixing step may lead to either synergistic effect or weakening the effect of the oil with MIC. It is better to use the MBC of the active one and preferably do not use such combinations. Better use two biologically active antibacterial oils.

Yes we can use it in combination of certain volums and concentrations and with using them in separate trials