Can we calculate binding constant for complexes having Ligand and metal in 3: 1 ratio using Benesi Hildebrand equation?

More Vishal Mutreja's questions See All

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

What could be the expression profile of alkaline phosphatase from lactic acid bacteria?

I have already cloned ALP gene of L rhamnosus into pET22b+ vector. Cloning is already confirmed by restriction digestion and sequencing. Cloning is achieved in BL21(DE3), Codon+, Rosetta and Lemo...

02 July 2024 5,332 3 View

Some samples show very good antibacterial properties in MIC estimation, but show no result in Disk diffusion method. Why?

Our plant extract samples have shown good results in MIC estimation proving that the compound is antibacterial. But on disk diffusion no proper result was seen. What could be the possible reason...

21 April 2024 240 8 View

How to choose and analyze current research papers in order to publish my own?

I have been by my institute to publish a research paper. As I have an ECE background, I am thinking to work on IoT. So please help me in choosing my topic and how to analyze other papers in order...

21 April 2024 9,299 2 View

Smart and effective real time management of street parking?

need an literature review

01 April 2024 5,273 0 View

Present your research @ Scopus/UGC Approved International Conference on Interdisciplinary Studies in Education Research & Technology 2024?

Dear Colleagues, It is indeed a pleasure to invite you to International Conference on Interdisciplinary Studies in Education Research & Technology 2024 (ISERT – 2024)...

11 February 2024 3,728 0 View

When I am doing scf calculation for PBE0 and HSE hybrid functional. my job is automatically terminated after convergence achieved ?

this is input file and i have attached small portion of error file and scf.out file &CONTROL calculation = 'scf' pseudo_dir = './' outdir = './tmp' prefix = 'DPSC' etot_conv_thr = 1e-5...

07 February 2024 5,404 1 View

Why sometimes we get a flipped pose when compared to original co-crystalized pose in PDB after molecular docking ?

Dear RG Community, I am validating my docking protocol by re-docking the co-crystalized ligand into a defined pocket. After docking, I am getting a pose which is flipped around its axis in 180...

11 December 2023 3,572 1 View

How to make MD movie from a large (.xtc) file.?

I am working on molecular docking and dynamic simulation of protein-ligand complex, and the complex generated MD.xtc file of 4.3 gb which I am unable to open in UCSF Chimera through MD movie...

26 November 2023 8,604 1 View

Where can I get solid state UV done for LaKMnO3 (expected band gap ~1 eV) sample, as normal UV-Vis spec doesn't work at that range?

Where can I obtain solid-state UV or DRS characterization in our country? LaMnO3 with K-substitution shows lower bandgap like that of LaSrMnO3 (LSMO). This material is black in colour and doesn't...

02 November 2023 1,652 0 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Why don't d-orbitals split themselves, why does it take a ligand? why don't protons from ligand repel nucleus split d-orbitals?

why don't d-orbitals split themselves because of themselves without the presence of ligands? Electrons are indistinguishable. Why wouldn't it be more correct that protons from a ligand split the...

03 August 2024 3,589 3 View

Why doesn't chromium 2+ ion use all its d-orbitals to receive lone pairs from six waters in [Cr(H20)6)]3+?

I'm guessing it's because the ligand experiences too much electron repulsion or proton repulsion from the chromium to insert them close to the 3d-orbitals which are close to the metal nucleus. Is...

03 August 2024 1,370 1 View

How can I find access to heavy metal reference doses from the EPA and WHO websites?

Reference dose and Maximum acceptable concentrations HMs

03 August 2024 8,230 4 View

How can you draw a coordinate bond between a metal and donor atom in metal complexes, using discovery studio visulizer software?

Hello,, The metal complex ligand appears incomplete in the screen of the discovery studio visualizer

30 July 2024 3,354 1 View

AutoGrid and Autodock 4.2.6 window opens for 1 second then closes and there is no output files?

Good day, I am a student trying to work on Autodock for a project regarding Ligand-DNA interaction so i am quite new to molecular docking. i have followed tutorials and did all the steps...

28 July 2024 2,136 4 View

How to determine LOD values?

I am performing fluorescence experiments using a ligand to detect metal ions. I want to determine the Lowest Detection Limit (LOD) using the formula LOD = 3σ / K. However, I'm uncertain about...

19 July 2024 1,086 1 View

Not able to give GAFF forcefield to my ligand?

I have been able to assign the CHARMM forcefield to my ligand i.e. acetyl coenzyme A but not the amber forcefield. I want to run amber forcefield and the parameterization of ligand is failing. I...

15 July 2024 7,323 1 View

Printing residues in an object in Pymol?

Hi! I am currently working on a protein where I have selected residues within 10A of its bound ligand in pymol. However, I can not find a way to print out what residues are contained in that group...

15 July 2024 1,727 1 View

How can we identify (in silico) the interacting amino acid residues or the nucleotides involved in the Protein-Protein / Protein-RNA interaction?

Hello! everyone, I am trying to study in silico Protein-Protein and Protein-RNA interactions. Now, is there any tool with which I can identify the interacting amino acid residues or the...

14 July 2024 950 2 View