What i have in mind is to know the epidemiology of these two infections since they seem to have similar vectors and present with fever
Thank you for your insight to my question. However, I am referring the infection in human subjects and not in the Vectors themselves. I mean the occurrence of co-infection of Yellow fever virus and Malaria in humans. May be i should add how do you screen for or diagnose if co-infection does exist?
Okay. Thanks
Looking forward to doing more work with you. could you forward your e-mail please?
Andefiki,
You've already gotten some good answers above, so I won't repeat too much. The important thing is to recognize that comparing an Anopheles mosquito to an Aedes mosquito is like comparing a cheetah to a lion. They are related and have some similarities, but they have radically different habits and characteristics in where they breed, how they develop, what the feed on, etc. So, epidemiologically the two diseases are radically different. Clinically, there is even greater difference. The fever is but one non-specific similarity, but other clinical aspects are entirely different. The two pathogens, virus and eukaryotic protist manipulate the body in profoundly different ways. Thus, they are very different both pathologically and immunologically. One aspect of this leads to the availability of an effective vaccine for YF, but not for malaria despite billions of dollars in research on the latter. In terms of someone being infected with both, of course this is possible. Currently YF has a limited distribution relative to malaria, and of course malaria exists in 5 different major forms (falciparum, vivax, malariae, ovale, knowlesi), each with different distribution and pathogenicities. So, with the current YF being more limited geographically, dual infections would be less common. However, YF is naturally a very widespread disease that has been temporarily restricted within the last several decades, only since the mid 1900s. As we are seeing recently in west Africa and Brazil, however, I predict that we may be nearing a major re-emergence of YF, If and when this happens, even if vivax malaria does not move back into temperate zones where it thrived in the 1800s (e.g., Italy and United States), we still would see more co-occurrence of YF and malaria than has been the case in recent decades.
I have linked to some publications that address some related issues. I hope you find them informative.
Best wishes,
Bruce
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Bruce,
Thanks a lot for the insight you have given. However, the links you mentioned were useful; could you please furnish me with your e-mail address for more collaborations? Thanks
Andefiki
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