Manganese peroxidase is a ligninolytic enzyme encoded by MnP genes in fungi. Expression of this gene is increased by Mn ions as substrate of MnP enzyme. Do manganese nanoparticles have any effect on mnp gene expression as well?
Dhinakarasamy Inbakandan
Dear Mojtaba Lotfi,
Normally Metal Nanoparticles will have impact on oxidative stress genes, in particular metallothionein genes. In your case, hope Manganese peroxidase kinetics in the presence of manganese nanoparticles itself is a good work. Further you can confirm it in your fungal model with enzyme production followed by gene expression studies in the presence and absence of NP.
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