I used Trizol to isolate RNA and then the DNAzol to isolate DNA from the interphase as suggested by the protocol. But the pellet of DNA is so hard that it is difficult to resuspend. Why should that be the case? Why should DNA be difficult to dissolve? The protocol suggests that the pellet be resuspended in 8mM NaOH to help dissolution, but this does not seem to help. This DNA is devoid of proteins and RNA. And I did not over-dry it.

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