I would like to use Lactic acid, Biotin labeled (HY-B2227F, MCE) for immunoprecipitation (IP). The presence of DMSO might interfere with the binding to the magnetic beads, so I would like to know the solubility of this product in water or PBS.
Hi，
Our measured solubility of HY-B2227F in H2O is ≥ 100 mg/mL.
High-purity DMSO may affect the performance of the magnetic beads. You can try preparing a stock solution with DMSO and then diluting it into your working solution. Also, perform a DMSO solvent control to eliminate any effects of DMSO on the magnetic bead performance. Based on experience with cell-based experiments, you can try keeping the DMSO content below 0.3%, which is highly likely to have no effect on the magnetic bead performance.
The answer to this question is provided by MedChemExpress Technical Support.
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