Can in-silico designed nanoparticles be validated in-silico or only via a wet-lab approach?
Thanks:)
Some relevant links are provided below.
a) journals.plos.org/plosone/article?id=10.1371/journal.pone.0159211
b) iopscience.iop.org/article/10.1088/0957-4484/27/44/445702/meta
c) Article Nanoinformatics: Emerging Databases and Available Tools
d) https://isp.ncifcrf.gov/library/publications/pdf/16.pdf
Hi Rajib and thank you for your kind update, I will read this helpful information.
Best,
Joel
Rabid I amended my original question, i.e. must in-silico be verified only via a wet-lab approach? (Or is there a possible in-silico validation?)
what can be the undiscovered benefits of applying telematic technologies for road pavement maintenance, incident reduction and environmental protection?
29 June 2024 7,507 1 View
most of the time when i search fo certain topic i found the human verification respond and nothing change there after
19 March 2024 6,870 0 View
Hello! I have a methodological question and I hope someone can help me. I collected data via an online survey with a sample size of 2600 (N = 2600). Initially, I aimed to examine the effect of...
26 February 2024 6,911 4 View
Hi RG Community I had input all the appropriate files, however, received an Action halted on error! My ORCA generated .gbw QM Output file was not recognized (please see screenshot attached). I...
15 February 2024 2,553 1 View
Typically, it is said that biofilter by their nature allow the settling of bacteria beneficial to the treatment of fishwaste. Fish culture though is known for producing high amounts of ammonia in...
28 January 2024 2,398 3 View
From what I can tell by searching the "Your World in Data" website, eastern Europe seems to have an expected lower than average all-cause mortality rate than the western first world nations, who...
04 January 2024 7,066 0 View
Hello RG Community:), I have a ligand exhibiting penalties between 10-50 within a .str file generated via a CGenFF, the generated .prm file does not exactly match the ligand atoms nor the closest...
25 December 2023 4,364 1 View
Hi I had modelled a heptamer transmembrane protein missing 10-residues within the extracellular loops via MODELLER constraining the known residues as a heptamer (when MODELLER modeled as a monomer...
08 December 2023 4,512 0 View
Hello towards the above topic, I successfully loop-modeled a transmembrane heptamer protein (426-residues per monomer) exhibiting 7-extracellular loops each missing 11-residues via MODELLER via...
03 December 2023 9,528 2 View
Need a simulation tool to generate synthetic data Specialized engine simulation software (for control and diagnosis) how and what to do 🙏?
16 November 2023 4,128 1 View
I am using Rhodamine6G as gain medium and silver nanoparticles as scatterers on a microscope slide and laser input 532 nm comes from above.
09 August 2024 9,894 2 View
A fungal strain was treated with nanoparticles. We want to do an environmental SEM analysis. So could anyone share your views on preparing the sample? Thank you.
07 August 2024 5,307 1 View
I have been using paraffin, but the deposited ZnO still detach from electrode. What is the best binder to modify graphite paste electrode with ZnO nanoparticles?
03 August 2024 4,624 3 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
Following curve related to Co0.6Mn0.4Fe2O4 Magnetic nanoparticles with extra phase a-Fe2O3. I will appreciate to help me to interpretation this spectroscopy, especially the blue line.
31 July 2024 9,140 2 View
I've attempted to use this method to synthesize copper nanoparticles. Copper nanoparticles can be synthesised using a variety of precursor materials. CuSO4, distilled water, NaOH, and EDTA are...
28 July 2024 8,027 3 View
How much volume of siRNA can I add to 2.5 mL of liposomes with a total lipid concentration of 10 mg/mL?
27 July 2024 6,920 1 View
Some of the techniques I am familiar with are standard. I would like to know which of the two methods under study is preferable, as well as the cost and list of particles and devices needed in...
22 July 2024 1,921 3 View
Is it the best optimization ratio based on experiments?
22 July 2024 8,170 0 View
What protocol can be used to measure the cellular uptake of a nanoparticle? Is there a way to get more of a non-targeted nanoparticle into the cell? Why a fluorescent nanoparticle does not enter...
18 July 2024 7,153 2 View