Can I measure bile acids and specifically cholic acid in plasma and tissue?

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Levans dose in vivo?

I would like to know what is the best dose of levan to use in vivo and the treatment period. I am using mice and I would like to gavage them with levans.

24 March 2021 8,113 4 View

Prebiotic administration to mice?

What is the best method for prebiotic delivery to mice? dose of prebiotics? and treatment period?

10 January 2021 7,595 6 View

Is it possible that an increase in central nerve system activity would lead to an increase in beta3 AR levels?

I was wondering if an increase in neurotransmitters such as NE will lead to an increase of B3AR expression?

08 July 2017 5,020 1 View

How to disrupt autophagy in vivo?

I was wondering if therer is any drug that disrupt autophgy in vivo. I would like to inject some transgenic mice with this drug and see how autophagy is affected. Thanks

29 March 2016 1,487 3 View

Can anyone suggest how to activate cathepsin in cells?

I would like to know how to activate cathepsin in cells.

31 January 2016 3,764 3 View

Is there any drug that causes in vivo ER stress induction without affecting the animal body weight?

I am using Tunicamycin as ER stress inducer in vivo and it is reducing the body weight a lot.

21 January 2015 7,592 0 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,101 4 View

Is there a problem with my RNA pellet?

Hello, I am currently having problems with RNA extraction. I am using mouse liver (C57BL6J), and I have extracted RNA from mouse liver before. Before this experiment, my final RNA pellets were...

11 August 2024 7,082 3 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Can you connect an HPLC to a Mass Spec only at a certain time point?

Can anyone explain this method? Especially the last statement where it says only at 1.5 to 2.5mins was the MS/MS connected to the UPLC. How is that possible, is it a feature in this specific...

11 August 2024 8,141 3 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,770 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,429 2 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View