Can anyone know best anticancer hydrophoic drug?

More Sudhakar Jinka's questions See All

How can i induce diabetes in cell lines?

i am synthesizing an anti-cancer drug but i am expecting that my may also work as anti-diabetic drug. so to induce diabetes in cell lines what should i do, which cell lines i have to take to...

07 August 2016 6,004 8 View

How to find out the mechanism of action of unknown drug without applying molecular modelling?

we have synthesized a drug in our lab. it is showing apoptotic and autophagic activity against cancer. but we don't know the exact mechanism. if anybody working on anti cancer therapies please...

06 July 2016 196 5 View

If anybody working on CRISPER: CAS9 please send best reviews and articles?

please send articles and reviews which are able to understand regarding CRISPER: CAS9 in relation with cancer

05 June 2016 2,488 0 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

For a case-control study for Breast Cancer incidents in a particular County in USA, what data can be used as Control? E.g. colorectal cancer?

The County health department is providing Breast cancer incident data. If colorectal cancer cases could be used as control, then we can get respective data from health department as well.

22 July 2024 9,954 4 View

About Machine Learning for Automated Diagnosis of Skin Cancer with Dermoscopy Images ?

Machine Learning for Automated Diagnosis of Skin Cancer with Dermoscopy Images

21 July 2024 5,471 0 View

How can I determine if a drug binds to a ribosome using a Cryo-EM map?

Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...

19 July 2024 2,155 0 View

Fixation Problem with cancer cells?

Hello everyone, I work with polyacrylamide hydrogels, which I fictionalise with sulfo-sanpa and collagen I to then plate lung cancer cells. The problem is that I lose a significant amount of...

19 July 2024 3,906 0 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

19 July 2024 8,522 0 View

Patrick Aouad

Dear Sudhakar,

Paclitaxel is a good example of hydrophobic chemotherapeutic agent.

Best,

Patrick

Rabbab Oun

Dear Sudhakar

I think one that is administered subcutaneously rather than intravenously would be the hydrophobic ones! so maybe search for drugs via their method of administration may help!

Goodluck

Ruby

Sudhakar Jinka

thanks both of you for the answers. we are already using paclitaxel. other than that i need.