Which suitable cell lines for studying Alzheimer's disease ? Thanks for answers in advance.
Alzheimer's disease (AD) is a complex disease and selection of a cell line for your study will depend upon which aspect of AD you plan to study. Although there are no "Alzheimer-formed" cell lines that I know of because most cell lines are from cancer patients or transformed cells you can read about neuronal cell lines such as IMR-32 or SH-SY5Y and SK-N-SH to find out which cell line you should start yiur work with. Good luck!
Please read carefully the manuscript and the reference to the manuscript in Attachment.
All the best.
I not am sure I quite understand what you mean by "Alzheimer-formed cell line".
Anyway, APPswe-N2a is neuro-2a cell line stably expressing the human APP Swedish double mutations at codons 670 and 671 of APP-770 in N2a cells. The Swedish mutation is a well-researched, if not the most-researched, Alzheimer's disease mutation. These cell lines are quite popular in the A.D research community and can easily be obtained from numerous scientists all over the world. So, I suggest you look for scientists working with these cell lines in countries around you and make a request from them, I am sure they will be glad to send you some vials because I don't know if these cell lines are commercially available. Good luck!
- Badges
- Science topic
- Similar topics
- Biological Science
- Molecular Cell Biology
- Culture Cells
- Cell Line