Can anybody provide information regarding ligand designing, especially for immune cells?

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Scheherazade Sadegh-Nasseri

Your question is extremely vague..ligands are made for receptors and I do not know which receptors you are targeting.

Sharif M. Shaheen

I am targeting CD40 and CD95 molecules, especially. .

Based on CD154/CD40 interactions I have designed a ligand theoretically but facing problem how to control the neutral amino acid length between two functional amino acids.